Fig 1: Oral quail egg treatment reduced the expressions of PAR-2 and NF-?B in tissues and promoted the cure of EoE like disease therapy (n = 5). (A) Immunohistochemistry of oesophagus, lung, and small intestine mice organ tissues. Scale bar 100 µm at 400×, (B) Immunohistochemical score analysis, (C) NF-?B p65 phosphorylation. Results are expressed as mean ± SEM. *P < 0.05 as compared to C group, #P < 0.05 as compared to P group.
Fig 2: PAR-2 and p-ERK expression in NS cHL. NS cHL (case #8). (A) H&E shows HRS cells and interspersed eosinophils and background fibrosis (inset, ×1000). (B) HRS cells shows membranous staining for CD30 and dim nuclear PAX-5 (inset, ×200). (C) HRS cells shows perinuclear expression of PAR-2 (inset, ×1000). (D) Semiquantitation of PAR-2 expression in NS cHL and other conditions. (E) HRS cells show nuclear p-ERK staining (inset, ×1000). (F) Semiquantitation of p-ERK expression in NS cHL and other conditions. Results are expressed as mean ± SEM (*P = 0.05). cHL = classic Hodgkin lymphoma; H&E = hematoxilin & eosin; HRS = Hodgkin/Reed-Sternberg cells; LD = lymphocyte-depleted; LR = lymphocyte-rich; MC = mixed-cellularity; ns, nonsignificant; NS = nodular sclerosis; p-ERK = phospho-extracellular signal-regulated kinase; PAR-2 = protease-activated receptor-2; SEM = standard error of the mean.
Supplier Page from Abcam for Anti-PAR2 antibody [SAM11]